Lombardy Region, situated in the North-West of Italy, is strategically located on principal European axes and is one of the leading regions both at the national and European level. Lombardy has a population of around 10 million inhabitants and a very competitive economic performance, with a GDP (PPS/inhabitant) which amounted to €39,700 in 2019 and an employment rate (20-64 years) of 73,4%. The regional economy is characterised by a wide variety of industries, ranging from traditional sectors to heavy and light industries. The production system is one of the most developed in Italy and Europe, with a strong presence of SMEs, except for a few very large firms. Entrepreneurship in Lombardy is thus widespread and dynamic, showing an international trend towards innovation, development, and technology. Lombardy also leads the way with a solid academic system of 14 high-quality universities as well as several public and private research centres with outstanding competence and international relevance. In such a context, the engagement of Lombardy in supporting R&D investments is intense and highly relevant. Innovation is indeed a distinguishing element of the region’s activities, being a driving force to ensure a competitive and modern socio-economic development.